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Journal of Cachexia, Sarcopenia and Muscle, 15(3), 455468

The mechanism of 6-paradol's thermogenic activity is activation of brown adipose tissue (BAT)

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However, none have yet been approved for the treatment of NASH, while many others have already been deemed ineffective (e.g., elafibranor, seladelpar, emricasan, selonsertib and elobixibat)

The strongest signals were seen in epigenetic measures linked to inflammation, brain, heart, blood, kidney, liver and metabolic health, suggesting that the drug may influence aging-related biology across multiple body systems